John R. Mascola, MD

Director / National Institute of Allergy and Infectious Diseases

National Institutes of Health, Vaccine Research Center 40 Convent Drive Bethesda, Maryland 20892

Dr. Mascola provides overall direction and scientific leadership to the basic, clinical, and translational research activities of the VRC. He oversees program operations, and recommends or develops new or revised research programs to meet public health needs.


John Mascola serves as a principal advisor to the director of NIAID on vaccines and related biomedical research affairs. He is also an expert consultant and advisor both nationally and internationally on the development of novel vaccine strategies against HIV, influenza, and other vaccines of high importance.

Research Interests

Dr. John Mascola’s laboratory research focuses on structure-informed vaccine design and antibody-mediated protective immune responses, including studies to understand the immunologic and immunogenetic characteristics that guide the development of neutralizing antibodies against viral pathogens.